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Team Focused Ultrasound – trial for Lewy body dementia

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Sir Jackie Stewart OBE

In partnership with the Focused Ultrasound Foundation, a medical research charity that funds research into the development of focused ultrasound, Race Against Dementia is funding a pioneering clinical trial to explore the potential of low-intensity focused ultrasound in improving cognitive function for people with Lewy body dementia.

Lewy body dementia is a complex and under-researched condition. It affects 15% of all dementia patients and is marked by progressive memory and attention impairment. With limited treatment options, there is an urgent need for fresh approaches to improve the lives of those affected.

Targeting cognitive decline in Lewy body dementia

The project, Improving cognition in Lewy body dementia using focused ultrasound, is led by Dr. Ashwini Oswal from the University of Oxford, with support from a team of experts across the university and from University College London.

Focused ultrasound has the potential to engage specific areas of the brain responsible for cognitive functions, offering a new avenue for treating Lewy body dementia. This study is the first clinical trial of its kind, making it a significant step in the search for innovative therapies.

A new approach to non-invasive brain treatments

This collaboration has been funded as part of Race Against Dementia’s £4.2 million funding programme run in partnership with medical research charity, Rosetrees. The initiative empowers groundbreaking research through grants of up to £750,000, with a focus on disruptive ideas and novel approaches.

Race Against Dementia Pull Quote

“Fast paced technology is the backbone of Formula 1, it drives performance, safety, and precision. Partnering with the Focused Ultrasound Foundation will enhance our endeavours to apply the same high-tech approach to dementia research and their focus on cutting-edge technology, will allow for the acceleration of solutions.”

Sir Jackie Stewart OBE, Race Against Dementia, Founder. 

Why this work is innovative

Focused ultrasound represents a non-invasive, targeted alternative to traditional treatments. Rather than using drugs, this technique harnesses sound waves to stimulate the brain, potentially improving cognitive functions with minimal risk and no surgery. If successful, this method could offer a rapid, accessible treatment option for people with Lewy body dementia and it is hoped the results pave the way for similar trials for other neurodegenerative conditions.

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WHAT IS DEMENTIA?

Dementia impacts memory, thinking and behaviour and includes several types of cognitive decline, such as Alzheimer’s disease, frontotemporal dementia, vascular dementia and Lewy body dementia.

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